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Preoperative Potassium Predicts Hyperkalemia Post-Parathyroidectomy

Hyperkalemia commonly occurs after parathyroidectomy (PTx) in patients on maintenance hemodialysis (HD), according to recent research. Now new study findings published in BMC Nephrology suggest...

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Parathyroid Hormone Predicts Fracture, Vascular Events, Death in CKD

In patients with chronic kidney disease (CKD) not on dialysis, elevated parathyroid hormone (PTH) levels correlate with an increased risk for fractures, vascular events, and death, Karen Hansen, MD,...

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Post-Parathyroidectomy Hungry Bone Syndrome Risk Factors ID’d

Hungry bone syndrome commonly occurs after parathyroidectomy with autotransplantation (PTx) in patients with secondary hyperparathyroidism on hemodialysis, and high preoperative serum alkaline...

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Holistic Approach to Managing SHPT Recommended for Older Adults

Little evidence exists on treating secondary hyperparathyroidism (SHPT) in adults older than 65 years. In a new review published in Drugs & Aging, the authors suggest nephrologists continue to...

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Calcitriol Loading May Not Prevent Post-PTx Hungry Bone Syndrome

Calcitriol loading before total parathyroidectomy (PTx) with autotransplantation in end-stage renal disease patients does not appear to prevent postoperative hypocalcemia, researchers of a small study...

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Study: Higher-Dose Dialysate Calcium Better for SHPT

In patients on peritoneal dialysis (PD), 1.75 vs 1.25 mmol/L dialysate calcium is more effective at treating secondary hyperparathyroidism (SHPT), but the 1.25 mmol/L dose is better at easing...

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Study: Adding Cinacalcet to Vitamin D Does Not Improve PTH

Cinacalcet in combination with vitamin D therapy has no effect on parathyroid hormone (PTH) levels in dialysis patients with secondary hyperparathyroidism (SHPT) compared with vitamin D alone, but the...

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Medication Use Low in Non-Dialysis CKD-MBD

Management of mineral bone disorders (MBD) in patients with non-dialysis chronic kidney disease (CKD) varies internationally, particularly with respect to target levels of biomarkers and use of...

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Earlier Parathyroidectomy May Ease Tumoral Calcinosis

Immediate parathyroidectomy (PTx) may be an effective treatment for hemodialysis patients with tumoral calcinosis due to secondary hyperparathyroidism (SHPT), according to investigators. Tumoral...

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Thermal Ablation, Parathyroidectomy Show Similar Efficacy in SHPT

Thermal ablation and parathyroidectomy (PTx) both effectively treat secondary hyperparathyroidism (SHPT), according to new research published in the International Journal of Surgery. In a...

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High Predialysis PTH Predicts Increased Risk for Uncontrolled PTH

WASHINGTON—Patients who have elevated parathyroid hormone (PTH) levels before the onset of end-stage renal disease are more likely to be prescribed active vitamin D and calcimimetic therapy after they...

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Guidance on Cinacalcet Use in Pediatric Dialysis

The FDA has not yet approved use of the calcimimetic cinacalcet in children receiving dialysis. In the absence of formal guidelines, the European Society for Paediatric Nephrology, Chronic Kidney...

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Timely Parathyroidectomy Urged in KTRs With Hyperparathyroidism

Timely parathyroidectomy (PTx) that avoids removal of too much parathyroid tissue may help preserve renal graft function among kidney transplant recipients with hyperparathyroidism by avoiding steep...

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Cinacalcet Effective in Young Children on Dialysis

Cinacalcet, a calcimimetic used to treat secondary hyperparathyroidism (SHPT) in adults, also appears relatively safe and effective for children younger than 5 years receiving maintenance dialysis,...

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Secondary Hyperparathyroidism Associated With Worsening Symptoms

Patients with secondary hyperparathyroidism (SHPT) experience worsening of certain symptoms as parathyroid hormone (PTH) levels increase, new data suggest. Investigators asked 165 patients with SHPT...

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SHPT Outcomes Similar for Oral Calcitriol vs IV Vitamin D

Switching from an intravenous (IV) vitamin D analog to oral calcitriol results in no worse outcomes in patients with secondary hyperparathyroidism (SHPT) on maintenance hemodialysis (HD), new study...

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New Calciphylaxis Risk Factor Identified

Unintentional weight loss, obesity, and use of vitamin K antagonists (VKA) are among the risk factors for calciphylaxis in patients on hemodialysis (HD), according to new study findings from a...

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High Levels of Calcium, Phosphate in SHPT Ups Death Risk

Hemodialysis (HD) patients with secondary hyperparathyroidism (SHPT) who have high serum calcium and phosphate levels have greater risks for death than patients with values in the normal range,...

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Denosumab May Slow Coronary Artery Calcification in Severe SHPT

Denosumab, an osteoporosis drug, may slow progression of coronary artery calcification (CAC) and potentially reverse osseous calcification in patients with secondary hyperparathyroidism (SHPT) who...

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Thrice-Weekly Cinacalcet Possibly Effective in HD

Administering the oral calcimimetic cinacalcet thrice weekly instead of once daily in hemodialysis (HD) patients may be effective for treating secondary hyperparathyroidism (SHPT), according to new...

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